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Cyclohexenyl nucleic acids: conformationally flexible oligonucleotides

Cyclohexenyl nucleic acid (CeNA) is a nucleic acid mimic, where the (deoxy)ribose sugar has been replaced by cyclohexenyl moieties. In order to study the conformation of cyclohexenyl nucleosides by NMR, the HexRot program was developed to calculate conformations from scalar coupling constants of cyc...

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Bibliografiske detaljer
Main Authors: Nauwelaerts, Koen, Lescrinier, Eveline, Sclep, Gert, Herdewijn, Piet
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1087899/
https://ncbi.nlm.nih.gov/pubmed/15863723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki538
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