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Cyclohexenyl nucleic acids: conformationally flexible oligonucleotides

Cyclohexenyl nucleic acid (CeNA) is a nucleic acid mimic, where the (deoxy)ribose sugar has been replaced by cyclohexenyl moieties. In order to study the conformation of cyclohexenyl nucleosides by NMR, the HexRot program was developed to calculate conformations from scalar coupling constants of cyc...

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Detalhes bibliográficos
Main Authors: Nauwelaerts, Koen, Lescrinier, Eveline, Sclep, Gert, Herdewijn, Piet
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1087899/
https://ncbi.nlm.nih.gov/pubmed/15863723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki538
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