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Direct observation of two cyclohexenyl (CeNA) ring conformations in duplex DNA

Cyclohexene Nucleic Acids (CeNA), in which the 2′-deoxyribofuranose ring of the DNA building blocks is substituted by a cyclohexenyl ring, were designed as potential mimics of natural nucleic acids for antisense and, later, for siRNA applications. CeNA units, in contrast to HNA (hexitol nucleic acid...

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Detalhes bibliográficos
Main Authors: Robeyns, Koen, Herdewijn, Piet, Van Meervelt, Luc
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3109440/
https://ncbi.nlm.nih.gov/pubmed/21687521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/adna.1.1.10952
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