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Direct observation of two cyclohexenyl (CeNA) ring conformations in duplex DNA
Cyclohexene Nucleic Acids (CeNA), in which the 2′-deoxyribofuranose ring of the DNA building blocks is substituted by a cyclohexenyl ring, were designed as potential mimics of natural nucleic acids for antisense and, later, for siRNA applications. CeNA units, in contrast to HNA (hexitol nucleic acid...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3109440/ https://ncbi.nlm.nih.gov/pubmed/21687521 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/adna.1.1.10952 |
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