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Cyclohexenyl nucleic acids: conformationally flexible oligonucleotides

Cyclohexenyl nucleic acid (CeNA) is a nucleic acid mimic, where the (deoxy)ribose sugar has been replaced by cyclohexenyl moieties. In order to study the conformation of cyclohexenyl nucleosides by NMR, the HexRot program was developed to calculate conformations from scalar coupling constants of cyc...

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Autori principali: Nauwelaerts, Koen, Lescrinier, Eveline, Sclep, Gert, Herdewijn, Piet
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1087899/
https://ncbi.nlm.nih.gov/pubmed/15863723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki538
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