Immunochemical studies of Shigella flexneri 2a and 6, and Shigella dysenteriae type 1 O-specific polysaccharide-core fragments and their protein conjugates as vaccine candidates

There is no licensed vaccine for the prevention of shigellosis. Our approach to the development of Shigella vaccine is based on inducing serum IgG antibodies to the O-specific polysaccharide (O-SP) domain of their lipopolysaccharides (LPS). We have shown that low molecular mass O-SP-core (O-SPC) fra...

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Main Authors: Kubler-Kielb, Joanna, Vinogradov, Evgeny, Mocca, Christopher, Pozsgay, Vince, Coxon, Bruce, Robbins, John B., Schneerson, Rachel
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2902686/
https://ncbi.nlm.nih.gov/pubmed/20542498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.carres.2010.05.006
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