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Mutagenic stress modulates the dynamics of CTG repeat instability associated with myotonic dystrophy type 1
The molecular basis of the myotonic dystrophy type 1 is the expansion of a CTG repeat at the DMPK locus. The expanded disease-associated repeats are unstable in both somatic and germ lines, with a high tendency towards expansion. The rate of expansion is directly related to the size of the pathogeni...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC290266/ https://ncbi.nlm.nih.gov/pubmed/14627806 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkg898 |
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