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RESIDUES IN THE MEMBRANE-SPANNING DOMAIN CORE MODULATE CONFORMATION AND FUSOGENICITY OF THE HIV-1 ENVELOPE GLYCOPROTEIN
The membrane-spanning domain (MSD) of Human Immunodeficiency Virus Type I (HIV-1) envelope glycoprotein (Env) is critical for its biological activity. Initial studies have defined an almost invariant “core” structure in the MSD and demonstrated that it is crucial for anchoring Env in the membrane an...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2902644/ https://ncbi.nlm.nih.gov/pubmed/20605619 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2010.03.016 |
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