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RESIDUES IN THE MEMBRANE-SPANNING DOMAIN CORE MODULATE CONFORMATION AND FUSOGENICITY OF THE HIV-1 ENVELOPE GLYCOPROTEIN

The membrane-spanning domain (MSD) of Human Immunodeficiency Virus Type I (HIV-1) envelope glycoprotein (Env) is critical for its biological activity. Initial studies have defined an almost invariant “core” structure in the MSD and demonstrated that it is crucial for anchoring Env in the membrane an...

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Bibliografische gegevens
Hoofdauteurs: Shang, Liang, Hunter, Eric
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2902644/
https://ncbi.nlm.nih.gov/pubmed/20605619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2010.03.016
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