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Characterizing the Murine Leukemia Virus Envelope Glycoprotein Membrane-Spanning Domain for Its Roles in Interface Alignment and Fusogenicity

The membrane-proximal region of murine leukemia virus envelope (Env) is a critical modulator of its functionality. We have previously shown that the insertion of one amino acid (+1 leucine) within the membrane-spanning domain (MSD) abolished protein functionality in infectivity assays. However, func...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Salamango, Daniel J., Johnson, Marc C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4665228/
https://ncbi.nlm.nih.gov/pubmed/26446598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01901-15
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