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Repair of single-strand DNA interruptions by redundant pathways and its implication in cellular sensitivity to DNA-damaging agents
Single-strand DNA interruptions (SSIs) are produced during the process of base excision repair (BER). Through biochemical studies, two SSI repair subpathways have been identified: a pathway mediated by DNA polymerase β (Pol β) and DNA ligase III (Lig III), and a pathway mediated by DNA polymerase δ/...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2003
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC290260/ https://ncbi.nlm.nih.gov/pubmed/14627836 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkg892 |
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