Telomeric allelic imbalance indicates defective DNA repair and sensitivity to DNA damaging agents

DNA repair competency is one determinant of sensitivity to certain chemotherapy drugs, such as cisplatin. Cancer cells with intact DNA repair can avoid the accumulation of genome damage during growth and also can repair platinum-induced DNA damage. We sought genomic signatures indicative of defectiv...

Cur síos iomlán

Na minha lista:
Sonraí Bibleagrafaíochta
Main Authors: Birkbak, Nicolai J., Wang, Zhigang C., Kim, Ji-Young, Eklund, Aron C., Li, Qiyuan, Tian, Ruiyang, Bowman-Colin, Christian, Li, Yang, Greene-Colozzi, April, Iglehart, J. Dirk, Tung, Nadine, Ryan, Paula D., Garber, Judy E., Silver, Daniel P., Szallasi, Zoltan, Richardson, Andrea L.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2012
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3806629/
https://ncbi.nlm.nih.gov/pubmed/22576213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-11-0206
Clibeanna: Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!

Míreanna Comhchosúla