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A Monte Carlo/Simulated Annealing Algorithm for Sequential Resonance Assignment in Solid State NMR of Uniformly Labeled Proteins with Magic-Angle Spinning

We describe a computational approach to sequential resonance assignment in solid state NMR studies of uniformly (15)N,(13)C-labeled proteins with magic-angle spinning. As input, the algorithm uses only the protein sequence and lists of (15)N/(13)C(α) crosspeaks from 2D NCACX and NCOCX spectra that i...

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Hlavní autoři: Tycko, Robert, Hu, Kan-Nian
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2902575/
https://ncbi.nlm.nih.gov/pubmed/20547467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmr.2010.05.013
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