Polyunsaturated fatty acids synergize with lipid droplet binding thalidomide analogs to induce oxidative stress in cancer cells

BACKGROUND: Cytoplasmic lipid-droplets are common inclusions of eukaryotic cells. Lipid-droplet binding thalidomide analogs (2,6-dialkylphenyl-4/5-amino-substituted-5,6,7-trifluorophthalimides) with potent anticancer activities were synthesized. RESULTS: Cytotoxicity was detected in different cell l...

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Bibliografiske detaljer
Main Authors: Puskás, László G, Fehér, Liliána Z, Vizler, Csaba, Ayaydin, Ferhan, Rásó, Erzsébet, Molnár, Eszter, Magyary, István, Kanizsai, Iván, Gyuris, Márió, Madácsi, Ramóna, Fábián, Gabriella, Farkas, Klaudia, Hegyi, Péter, Baska, Ferenc, Ózsvári, Béla, Kitajka, Klára
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2010
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2902471/
https://ncbi.nlm.nih.gov/pubmed/20525221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-511X-9-56
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