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Polyunsaturated fatty acids synergize with lipid droplet binding thalidomide analogs to induce oxidative stress in cancer cells

BACKGROUND: Cytoplasmic lipid-droplets are common inclusions of eukaryotic cells. Lipid-droplet binding thalidomide analogs (2,6-dialkylphenyl-4/5-amino-substituted-5,6,7-trifluorophthalimides) with potent anticancer activities were synthesized. RESULTS: Cytotoxicity was detected in different cell l...

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Detaylı Bibliyografya
Asıl Yazarlar: Puskás, László G, Fehér, Liliána Z, Vizler, Csaba, Ayaydin, Ferhan, Rásó, Erzsébet, Molnár, Eszter, Magyary, István, Kanizsai, Iván, Gyuris, Márió, Madácsi, Ramóna, Fábián, Gabriella, Farkas, Klaudia, Hegyi, Péter, Baska, Ferenc, Ózsvári, Béla, Kitajka, Klára
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2902471/
https://ncbi.nlm.nih.gov/pubmed/20525221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-511X-9-56
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