Polyunsaturated fatty acids synergize with lipid droplet binding thalidomide analogs to induce oxidative stress in cancer cells

BACKGROUND: Cytoplasmic lipid-droplets are common inclusions of eukaryotic cells. Lipid-droplet binding thalidomide analogs (2,6-dialkylphenyl-4/5-amino-substituted-5,6,7-trifluorophthalimides) with potent anticancer activities were synthesized. RESULTS: Cytotoxicity was detected in different cell l...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Puskás, László G, Fehér, Liliána Z, Vizler, Csaba, Ayaydin, Ferhan, Rásó, Erzsébet, Molnár, Eszter, Magyary, István, Kanizsai, Iván, Gyuris, Márió, Madácsi, Ramóna, Fábián, Gabriella, Farkas, Klaudia, Hegyi, Péter, Baska, Ferenc, Ózsvári, Béla, Kitajka, Klára
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2010
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2902471/
https://ncbi.nlm.nih.gov/pubmed/20525221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-511X-9-56
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