Optimization and analysis of a quantitative real-time PCR-based technique to determine microRNA expression in formalin-fixed paraffin-embedded samples

BACKGROUND: MicroRNAs (miRs) are non-coding RNA molecules involved in post-transcriptional regulation, with diverse functions in tissue development, differentiation, cell proliferation and apoptosis. miRs may be less prone to degradation during formalin fixation, facilitating miR expression studies...

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Detalhes bibliográficos
Main Authors: Goswami, Rashmi S, Waldron, Levi, Machado, Jerry, Cervigne, Nilva K, Xu, Wei, Reis, Patricia P, Bailey, Denis J, Jurisica, Igor, Crump, Michael R, Kamel-Reid, Suzanne
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Methodology article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2902407/
https://ncbi.nlm.nih.gov/pubmed/20573258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-10-47
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