Excision repair is required for genotoxin-induced mutagenesis in mammalian cells

Certain hexavalent chromium [Cr(VI)] compounds are human lung carcinogens. Although much is known about Cr-induced DNA damage, very little is known about mechanisms of Cr(VI) mutagenesis and the role that DNA repair plays in this process. Our goal was to investigate the role of excision repair (ER)...

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Bibliografiset tiedot
Päätekijät: Brooks, Bradford, O'Brien, Travis J., Ceryak, Susan, Wise, John Pierce, Wise, Sandra S., DeFabo, Edward, Patierno, Steven R.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2008
Aiheet:
Carcinogenesis
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2902384/
https://ncbi.nlm.nih.gov/pubmed/18332048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgn058
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