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Melt-in-Mouth Pellets of Fexofenadine Hydrochloride Using Crospovidone as an Extrusion–Spheronisation Aid

Microcrystalline cellulose (MCC) is well established as an extrusion spheronisation aid for the preparation of pellets. Crospovidone (Polyplasdone® XL-10) is compared with microcrystalline cellulose for the preparation of melt-in-mouth pellets. Taste-masked fexofenadine hydrochloride was incorporate...

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Detalhes bibliográficos
Main Authors: Jain, Satishkumar P., Mehta, Dharmini C., Shah, Sejal P., Singh, Pirthi Pal, Amin, Purnima D.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2902318/
https://ncbi.nlm.nih.gov/pubmed/20499219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-010-9443-7
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