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Use of Placket–Burman Statistical Design to Study Effect of Formulation Variables on the Release of Drug from Hot Melt Sustained Release Extrudates
The present paper was focused on exploiting Plackett–Burman design to screen the effect of nine factors—poly (ethylene oxide) molecular weight (X(1)), poly (ethylene oxide) amount (X(2)), ethylcellulose amount (X(4)), drug solubility (X(5)), drug amount (X(6)), sodium chloride amount (X(7)), citric...
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| Huvudupphovsmän: | , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Springer US
2010
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2902313/ https://ncbi.nlm.nih.gov/pubmed/20509057 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-010-9444-6 |
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