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Development and In Vitro Characterization of Galactosylated Low Molecular Weight Chitosan Nanoparticles Bearing Doxorubicin

The aim of the present research was to evaluate the potential of galactosylated low molecular weight chitosan (Gal-LMWC) nanoparticles bearing positively charged anticancer, doxorubicin (DOX) for hepatocyte targeting. The chitosan from crab shell was depolymerized, and the lactobionic acid was coupl...

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Detalhes bibliográficos
Main Authors: Jain, Nitin K., Jain, Sanjay K.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2902311/
https://ncbi.nlm.nih.gov/pubmed/20414758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-010-9422-z
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