Llwytho...

Autophagy induced by Alexander disease-mutant GFAP accumulation is regulated by p38/MAPK and mTOR signaling pathways

Glial fibrillary acidic protein (GFAP) is the principle intermediate filament (IF) protein in astrocytes. Mutations in the GFAP gene lead to Alexander disease (AxD), a rare, fatal neurological disorder characterized by the presence of abnormal astrocytes that contain GFAP protein aggregates, termed...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Tang, Guomei, Yue, Zhenyu, Talloczy, Zsolt, Hagemann, Tracy, Cho, Woosung, Messing, Albee, Sulzer, David L., Goldman, James E.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2008
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2902290/
https://ncbi.nlm.nih.gov/pubmed/18276609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddn042
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!