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Teaching old receptors new tricks: biasing seven-transmembrane receptors
Seven-transmembrane receptors (7TMRs; also known as G protein-coupled receptors) are the largest class of receptors in the human genome and are common targets for therapeutics. Originally identified as mediators of 7TMR desensitization, β-arrestins (arrestin 2 and arrestin 3) are now recognized as t...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2902265/ https://ncbi.nlm.nih.gov/pubmed/20431569 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrd3024 |
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