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Na(V)1.1 channels and epilepsy
Voltage-gated sodium channels initiate action potentials in brain neurons, and sodium channel blockers are used in therapy of epilepsy. Mutations in sodium channels are responsible for genetic epilepsy syndromes with a wide range of severity, and the Na(V)1.1 channel encoded by the SCN1A gene is the...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Blackwell Science Inc
2010
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2901973/ https://ncbi.nlm.nih.gov/pubmed/20194124 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2010.187484 |
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