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Sodium channel gene family: epilepsy mutations, gene interactions and modifier effects

The human sodium channel family includes seven neuronal channels that are essential for the initiation and propagation of action potentials in the CNS and PNS. In view of their critical role in neuronal firing and their strong sequence conservation during evolution, it is not surprising that mutatio...

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Detalhes bibliográficos
Main Authors: Meisler, Miriam H, O’Brien, Janelle E, Sharkey, Lisa M
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2901972/
https://ncbi.nlm.nih.gov/pubmed/20351042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2010.188482
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