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Expression, Glycoform Characterization, and Antibody-binding of HIV-1 V3 Glycopeptide Domain Fused with Human IgG1-Fc

The third variable domain (V3) of HIV-1 gp120 envelope glycoprotein is critical for HIV-1 entry and represents an attractive target for vaccine design. There are three conserved N-glycans within or around the V3 loop. The N295 and N332 glycans at the base of V3 are usually characterized as high-mann...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Yang, Qiang, Li, Cishan, Wei, Yadong, Huang, Wei, Wang, Lai-Xi
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2901909/
https://ncbi.nlm.nih.gov/pubmed/20369886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc9004238
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