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Cellular phenotype transformation occurs during thoracic aortic aneurysm development

OBJECTIVE: Thoracic aortic aneurysms (TAAs) result from dysregulated remodeling of the vascular extracellular matrix (ECM) which may occur as a result of altered resident cellular function. The present study tested the hypothesis that aortic fibroblasts undergo a stable change in cellular phenotype...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Jones, Jeffrey A., Zavadzkas, Juozas A., Chang, Eileen I., Sheats, Nina, Koval, Christine, Stroud, Robert E., Spinale, Francis G., Ikonomidis, John S
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2901416/
https://ncbi.nlm.nih.gov/pubmed/20219212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtcvs.2009.12.033
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