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Cellular phenotype transformation occurs during thoracic aortic aneurysm development

OBJECTIVE: Thoracic aortic aneurysms (TAAs) result from dysregulated remodeling of the vascular extracellular matrix (ECM) which may occur as a result of altered resident cellular function. The present study tested the hypothesis that aortic fibroblasts undergo a stable change in cellular phenotype...

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Detalhes bibliográficos
Main Authors: Jones, Jeffrey A., Zavadzkas, Juozas A., Chang, Eileen I., Sheats, Nina, Koval, Christine, Stroud, Robert E., Spinale, Francis G., Ikonomidis, John S
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2901416/
https://ncbi.nlm.nih.gov/pubmed/20219212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtcvs.2009.12.033
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