Altered Transforming Growth Factor-beta Signaling in a Murine Model of Thoracic Aortic Aneurysm

OBJECTIVE: Thoracic aortic aneurysms (TAAs) develop by a multifactorial process involving maladaptive signaling pathways which alter the aortic vascular environment. Transforming growth factor-beta (TGF-β) has been implicated in regulating the structure and composition of the extracellular matrix by...

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Hauptverfasser: Jones, Jeffrey A., Barbour, John R., Stroud, Robert E., Bouges, Shenikqua, Stephens, Shelly L., Spinale, Francis G., Ikonomidis, John S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2574785/
https://ncbi.nlm.nih.gov/pubmed/18434745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000127437
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