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Neuropeptidomic Analysis Establishes a Major Role for Prohormone Convertase-2 in Neuropeptide Biosynthesis

Prohormone convertase 2 (PC2) functions in the generation of neuropeptides from their precursors. A quantitative peptidomics approach was used to evaluate the role of PC2 in the processing of peptides in a variety of brain regions. Altogether, 115 neuropeptides or other peptides derived from secreto...

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Main Authors: Zhang, Xin, Pan, Hui, Peng, Bonnie, Steiner, Donald F., Pintar, John E., Fricker, Lloyd D.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2901178/
https://ncbi.nlm.nih.gov/pubmed/19968759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2009.06530.x
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