DEXAMETHASONE AND CORTICOSTERONE INDUCE SIMILAR, BUT NOT IDENTICAL, MUSCLE WASTING RESPONSES IN CULTURED L6 AND C2C12 MYOTUBES

Dexamethasone-treated L6 (a rat cell line) and C2C12 (a mouse cell line) myotubes are frequently used as in vitro models of muscle wasting. We compared the effects of different concentrations of dexamethasone and corticosterone (the naturally occurring glucocorticoid in rodents) on protein breakdown...

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Bibliographic Details
Main Authors: Menconi, Michael, Gonnella, Patricia, Petkova, Victoria, Lecker, Stewart, Hasselgren, Per-Olof
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2901105/
https://ncbi.nlm.nih.gov/pubmed/18615595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.21833
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