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PI3 kinase signalling blocks Foxp3 expression by sequestering Foxo factors

Expression of the regulatory T (T reg) cell–associated transcription factor Foxp3 can be induced by signals from the T cell receptor (TCR), interleukin-2 (IL-2), and transforming growth factor (TGF)-β. These signals are integrated by a network involving phosphatidylinositol 3 kinase (PI3K), protein...

詳細記述

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書誌詳細
主要な著者: Merkenschlager, Matthias, von Boehmer, Harald
フォーマット: Artigo
言語:Inglês
出版事項: The Rockefeller University Press 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2901062/
https://ncbi.nlm.nih.gov/pubmed/20603315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20101156
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