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On Relevance of Codon Usage to Expression of Synthetic and Natural Genes in Escherichia coli

A recent investigation concluded that codon bias did not affect expression of green fluorescent protein (GFP) variants in Escherichia coli, while stability of an mRNA secondary structure near the 5′ end played a dominant role. We demonstrate that combining the two variables using regression trees or...

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Bibliografske podrobnosti
Main Authors: Supek, Fran, Šmuc, Tomislav
Format: Artigo
Jezik:Inglês
Izdano: Genetics Society of America 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2900969/
https://ncbi.nlm.nih.gov/pubmed/20421604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.110.115477
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