Arginase I–Producing Myeloid-Derived Suppressor Cells in Renal Cell Carcinoma Are a Subpopulation of Activated Granulocytes

Myeloid-derived suppressor cells (MDSC) producing arginase I are increased in the peripheral blood of patients with renal cell carcinoma (RCC). MDSC inhibit T-cell function by reducing the availability of l-arginine and are therefore considered an important tumor escape mechanism. We aimed to determ...

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Hlavní autoři: Rodriguez, Paulo C., Ernstoff, Marc S., Hernandez, Claudia, Atkins, Michael, Zabaleta, Jovanny, Sierra, Rosa, Ochoa, Augusto C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2900845/
https://ncbi.nlm.nih.gov/pubmed/19201693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-1921
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