Mouse MOV10L1 associates with Piwi proteins and is an essential component of the Piwi-interacting RNA (piRNA) pathway

Piwi-interacting RNAs (piRNAs) are essential for silencing of transposable elements in the germline, but their biogenesis is poorly understood. Here we demonstrate that MOV10L1, a germ cell–specific putative RNA helicase, is associated with Piwi proteins. Genetic disruption of the MOV10L1 RNA helica...

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Bibliographische Detailangaben
Hauptverfasser: Zheng, Ke, Xiol, Jordi, Reuter, Michael, Eckardt, Sigrid, Leu, N. Adrian, McLaughlin, K. John, Stark, Alexander, Sachidanandam, Ravi, Pillai, Ramesh S., Wang, Peijing Jeremy
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2010
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2900664/
https://ncbi.nlm.nih.gov/pubmed/20534472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1003953107
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