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The ubiquitin ligase Fbxw7 controls adipocyte differentiation by targeting C/EBPα for degradation
Adipose tissue controls body lipid and energy metabolism, as well as food intake, and abnormalities in adipose function play a central role in diseases such as obesity and type-2 diabetes. Adipocyte differentiation is controlled by a transcriptional cascade involving PPARγ and members of the C/EBP f...
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| Autores principales: | , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2900639/ https://ncbi.nlm.nih.gov/pubmed/20534483 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0913367107 |
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