Structures of actin-bound Wiskott-Aldrich syndrome protein homology 2 (WH2) domains of Spire and the implication for filament nucleation

Three classes of proteins are known to nucleate new filaments: the Arp2/3 complex, formins, and the third group of proteins that contain ca. 25 amino acid long actin-binding Wiskott-Aldrich syndrome protein homology 2 domains, called the WH2 repeats. Crystal structures of the complexes between the a...

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Hauptverfasser: Ducka, Anna M., Joel, Peteranne, Popowicz, Grzegorz M., Trybus, Kathleen M., Schleicher, Michael, Noegel, Angelika A., Huber, Robert, Holak, Tad A., Sitar, Tomasz
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2010
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2900636/
https://ncbi.nlm.nih.gov/pubmed/20538977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1005347107
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