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Structural basis for the inhibition of insulin-like growth factors by insulin-like growth factor-binding proteins
Insulin-like growth factor-binding proteins (IGFBPs) control bioavailability, activity, and distribution of insulin-like growth factor (IGF)1 and -2 through high-affinity IGFBP/IGF complexes. IGF-binding sites are found on N- and C-terminal fragments of IGFBPs, the two conserved domains of IGFBPs. T...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1551901/ https://ncbi.nlm.nih.gov/pubmed/16924115 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0605652103 |
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