Structural basis for the inhibition of insulin-like growth factors by insulin-like growth factor-binding proteins

Insulin-like growth factor-binding proteins (IGFBPs) control bioavailability, activity, and distribution of insulin-like growth factor (IGF)1 and -2 through high-affinity IGFBP/IGF complexes. IGF-binding sites are found on N- and C-terminal fragments of IGFBPs, the two conserved domains of IGFBPs. T...

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Main Authors: Sitar, Tomasz, Popowicz, Grzegorz M., Siwanowicz, Igor, Huber, Robert, Holak, Tad A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2006
Ábhair:
Biological Sciences
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1551901/
https://ncbi.nlm.nih.gov/pubmed/16924115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0605652103
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