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Nuclear EGFR Contributes to Acquired Resistance to Cetuximab

Epidermal growth factor receptor (EGFR) is a ubiquitously expressed receptor tyrosine kinase involved in the etiology of several human cancers. Cetuximab is an EGFR blocking-antibody that has been approved for the treatment of patients with cancers of the head and neck (HNSCC) and metastatic colorec...

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Hlavní autoři: Li, Chunrong, Iida, Mari, Dunn, Emily F., Ghia, Amol J., Wheeler, Deric L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2900381/
https://ncbi.nlm.nih.gov/pubmed/19684613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2009.234
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