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TOPO3α Influences Antigenic Variation by Monitoring Expression-Site-Associated VSG Switching in Trypanosoma brucei

Homologous recombination (HR) mediates one of the major mechanisms of trypanosome antigenic variation by placing a different variant surface glycoprotein (VSG) gene under the control of the active expression site (ES). It is believed that the majority of VSG switching events occur by duplicative gen...

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Detalhes bibliográficos
Main Authors: Kim, Hee-Sook, Cross, George A. M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2900300/
https://ncbi.nlm.nih.gov/pubmed/20628569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000992
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