Lataa...
Targeting Human Gastrointestinal Stromal Tumour Cells with a Quadruplex-binding Small Molecule
The majority of human gastrointestinal stromal tumours (GIST) are driven by activating mutations in the proto-oncogene KIT, a tyrosine kinase receptor. Clinical treatment with imatinib targets the kinase domain of KIT, but tumour regrowth occurs as a result of the development of resistant mutations...
Tallennettuna:
| Päätekijät: | , , , , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2009
|
| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2900250/ https://ncbi.nlm.nih.gov/pubmed/19469547 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm900424a |
| Tagit: |
Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!
|