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Loop flexibility in human telomeric quadruplex small-molecule complexes
Quadruplex nucleic acids can be formed at the ends of eukaryotic chromosomes. Their formation and stabilisation by appropriate small molecules can be used as a means of inhibiting the telomere maintenance functions of telomerase in human cancer cells. The crystal structures have been determined for...
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| Veröffentlicht in: | Nucleic Acids Res |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4446451/ https://ncbi.nlm.nih.gov/pubmed/25940631 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv427 |
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