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TFIIA and the transactivator Rap1 cooperate to commit TFIID for transcription initiation
Transcription of eukaryotic mRNA encoding genes by RNA polymerase II (Pol II) is triggered by the binding of transactivating proteins to enhancer DNA, which stimulates the recruitment of general transcription factors (GTFs; TFIIA, B, D, E, F, H) and Pol II on the cis-linked promoter leading to prein...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2900199/ https://ncbi.nlm.nih.gov/pubmed/20559389 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09080 |
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