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TFIIA and the transactivator Rap1 cooperate to commit TFIID for transcription initiation

Transcription of eukaryotic mRNA encoding genes by RNA polymerase II (Pol II) is triggered by the binding of transactivating proteins to enhancer DNA, which stimulates the recruitment of general transcription factors (GTFs; TFIIA, B, D, E, F, H) and Pol II on the cis-linked promoter leading to prein...

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Bibliografische gegevens
Hoofdauteurs: Papai, Gabor, Tripathi, Manish K., Ruhlmann, Christine, Layer, Justin H., Weil, P. Anthony, Schultz, Patrick
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2900199/
https://ncbi.nlm.nih.gov/pubmed/20559389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09080
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