TFIIA and the transactivator Rap1 cooperate to commit TFIID for transcription initiation

Transcription of eukaryotic mRNA encoding genes by RNA polymerase II (Pol II) is triggered by the binding of transactivating proteins to enhancer DNA, which stimulates the recruitment of general transcription factors (GTFs; TFIIA, B, D, E, F, H) and Pol II on the cis-linked promoter leading to prein...

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Bibliographic Details
Main Authors: Papai, Gabor, Tripathi, Manish K., Ruhlmann, Christine, Layer, Justin H., Weil, P. Anthony, Schultz, Patrick
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2900199/
https://ncbi.nlm.nih.gov/pubmed/20559389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09080
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