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TFIIA and the transactivator Rap1 cooperate to commit TFIID for transcription initiation

Transcription of eukaryotic mRNA encoding genes by RNA polymerase II (Pol II) is triggered by the binding of transactivating proteins to enhancer DNA, which stimulates the recruitment of general transcription factors (GTFs; TFIIA, B, D, E, F, H) and Pol II on the cis-linked promoter leading to prein...

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Hlavní autoři: Papai, Gabor, Tripathi, Manish K., Ruhlmann, Christine, Layer, Justin H., Weil, P. Anthony, Schultz, Patrick
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2900199/
https://ncbi.nlm.nih.gov/pubmed/20559389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09080
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