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Ambiguities in applying traditional Limulus Amoebocyte Lysate tests to quantify endotoxin in nanoparticle formulations

Nanotechnology is finding increasing application in biology and medicine. As with other pharmaceutical formulations and medical devices intended for use in animals and human patients, contamination of nanoparticles with bacterial endotoxins should be thoroughly investigated before preclinical in vit...

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Bibliographic Details
Main Authors: Dobrovolskaia, Marina A, Neun, Barry W, Clogston, Jeffrey D, Ding, Hui, Ljubimova, Julia, McNeil, Scott E
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2900157/
https://ncbi.nlm.nih.gov/pubmed/20528451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/nnm.10.29
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