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Ambiguities in applying traditional Limulus Amoebocyte Lysate tests to quantify endotoxin in nanoparticle formulations

Nanotechnology is finding increasing application in biology and medicine. As with other pharmaceutical formulations and medical devices intended for use in animals and human patients, contamination of nanoparticles with bacterial endotoxins should be thoroughly investigated before preclinical in vit...

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Hlavní autoři: Dobrovolskaia, Marina A, Neun, Barry W, Clogston, Jeffrey D, Ding, Hui, Ljubimova, Julia, McNeil, Scott E
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2900157/
https://ncbi.nlm.nih.gov/pubmed/20528451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/nnm.10.29
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