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Interplay between Cdh1 and JNK activity during the cell cycle
The ubiquitin ligase APC/C(Cdh1) coordinates degradation of key cell cycle regulators. We report here that a nuclear-localized portion of the stress-activated kinase JNK is degraded by the APC/C(Cdh1) during exit from mitosis and G1 phase of the cell cycle. Expression of a non-degradable JNK induces...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2899685/ https://ncbi.nlm.nih.gov/pubmed/20581839 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2071 |
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