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Control of p53 multimerization by Ubc13 is JNK-regulated

The p53 tumor suppressor protein is a key regulator of cellular proliferation and survival whose function is tightly regulated at the levels of transcription and protein stability. Here, we unveil the fine control of p53 on translationally active polysomes. We have previously reported that Ubc13, an...

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Autores principales: Topisirovic, Ivan, Gutierrez, Gustavo J., Chen, Meifan, Appella, Ettore, Borden, Katherine L. B., Ronai, Ze'ev A.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2722327/
https://ncbi.nlm.nih.gov/pubmed/19651615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0900596106
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