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Tracing the origins and signatures of selection of antifolate resistance in island populations of Plasmodium falciparum

BACKGROUND: Resistance of the malaria parasite Plasmodium falciparum to sulfadoxine-pyrimethamine (SP) has evolved worldwide. In the archipelago of São Tomé and Principe (STP), West Africa, although SP resistance is highly prevalent the drug is still in use in particular circumstances. To address th...

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書誌詳細
主要な著者: Salgueiro, Patrícia, Vicente, José L, Ferreira, Conceição, Teófilo, Vânia, Galvão, André, do Rosário, Virgílio E, Cravo, Pedro, Pinto, João
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2898820/
https://ncbi.nlm.nih.gov/pubmed/20534146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2334-10-163
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