Independent Origin of Plasmodium falciparum Antifolate Super-Resistance, Uganda, Tanzania, and Ethiopia

Super-resistant Plasmodium falciparum threatens the effectiveness of sulfadoxine–pyrimethamine in intermittent preventive treatment for malaria during pregnancy. It is characterized by the A581G Pfdhps mutation on a background of the double-mutant Pfdhps and the triple-mutant Pfdhfr. Using samples c...

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Detalhes bibliográficos
Main Authors: Alifrangis, Michael, Nag, Sidsel, Schousboe, Mette L., Ishengoma, Deus, Lusingu, John, Pota, Hirva, Kavishe, Reginald A., Pearce, Richard, Ord, Rosalynn, Lynch, Caroline, Dejene, Seyoum, Cox, Jonathan, Rwakimari, John, Minja, Daniel T.R., Lemnge, Martha M., Roper, Cally
Formato: Artigo
Idioma:Inglês
Publicado em: Centers for Disease Control and Prevention 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4111169/
https://ncbi.nlm.nih.gov/pubmed/25061906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3201/eid2008.131897
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