Myeloperoxidase-rich Ly-6C(+) myeloid cells infiltrate allografts and contribute to an imaging signature of organ rejection in mice

Rates of graft rejection are high among recipients of heart transplants. The onset and progression of clinically significant heart transplant rejection are currently monitored by serial biopsy, but this approach is highly invasive and lacks sensitivity. Here, we have developed what we believe to be...

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Autori principali: Swirski, Filip K., Wildgruber, Moritz, Ueno, Takuya, Figueiredo, Jose-Luiz, Panizzi, Peter, Iwamoto, Yoshiko, Zhang, Elizabeth, Stone, James R., Rodriguez, Elisenda, Chen, John W., Pittet, Mikael J., Weissleder, Ralph, Nahrendorf, Matthias
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2010
Soggetti:
Technical Advance
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2898607/
https://ncbi.nlm.nih.gov/pubmed/20577051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI42304
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