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Vasculitis: Molecular Imaging by Targeting the Inflammatory Enzyme Myeloperoxidase

PURPOSE: To determine if a molecular imaging approach targeting the highly oxidative enzyme myeloperoxidase (MPO) can help noninvasively identify and confirm sites of vascular wall inflammation in a murine model of vasculitis. MATERIALS AND METHODS: Animal experiments were approved by the institutio...

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Detalhes bibliográficos
Main Authors: Su, Henry S., Nahrendorf, Matthias, Panizzi, Peter, Breckwoldt, Michael O., Rodriguez, Elisenda, Iwamoto, Yoshiko, Aikawa, Elena, Weissleder, Ralph, Chen, John W.
Formato: Artigo
Idioma:Inglês
Publicado em: Radiological Society of North America, Inc. 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3244672/
https://ncbi.nlm.nih.gov/pubmed/22084204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1148/radiol.11110040
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